New Zealand: Rua Bioscience joins partnership to protect, develop New Zealand’s cannabinoid-producing liverwort

MMJ Daily

Rua Bioscience has entered into a joint venture between three companies and an entity representing the interests of an indigenous plant. This is important step for Indigenous-led science in Aotearoa.

At the center of the venture is Wairuakohu (Radula marginata), a liverwort endemic to Aotearoa. Found in native forests across the North Island and on some offshore islands, this unassuming plant has been around nearly 400 million years and grows only around 1mm a month, yet it holds something pretty special.

Wairuakohu produces rare bibenzyl cannabinoids, including perrottetinene (PET), a molecule very similar to THC, one of the main secondary metabolites of Cannabis Sativa. 2018 Research showed synthesized PET could cross the blood-brain barrier in mice, producing cooling and pain-relieving effects. It demonstrates benefits similar to THC without some of the side effects of THC.

Rua’s co-founder Manu Caddie recognized this potential early on and made the case for Rua to invest in the Wairuakohu research nearly ten years ago, grounded in our commitment to cannabinoid medicines and Indigenous innovation.

That early investment helped lay the foundation for the work that continues today and was formalized recently with the signing of a limited partnership between the Wairuakohu Charitable Trust, an entity established to protect and benefit the species that is governed by iwi (Māori tribal authorities) that have the plant growing in their territories, and research and development investors, Rua Bioscience, the Bioeconomy Science Institute, and IO Limited (Manu’s own company).

Protecting the taonga (treasured indigenous species) and the ecosystems that sustains it is central to the project, and the Wairuakohu Charitable Trust therefore represents the interests of the plant and its customary kaitiaki, holding a 50% shareholding in the venture, ensuring any future benefits from commercialising intellectual property held by the venture are shared equitably.

“We’re grateful to have played a part in getting this kaupapa off the ground, and excited to see this kaitiaki-led approach to research and innovation continue to grow,” said Rua Bioscience in a statement.

https://www.mmjdaily.com/article/9863256/rua-bioscience-joins-partnership-to-protect-develop-new-zealand-s-cannabinoid-producing-liverwort/

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