Media reports say that he FDA did not immediately confirm his resignation.

The Washington Post broke the story

FDA Commissioner Gottlieb, who raised alarms about teen vaping, resigns

https://www.washingtonpost.com/health/2019/03/05/fda-commissioner-gottlieb-who-raised-alarms-about-teen-vaping-resigns/?utm_term=.fe0002d4ddaf

Gottlieb, who has been commuting weekly to Washington from his home in Connecticut, wants to spend more time with his family, the official said. The 46-year-old physician, millionaire venture capitalist and cancer survivor known for a self-assured, sometimes brash, manner lives in Westport, with his wife and three daughters – 9-year-old twins and a 5-year-old.

The resignation was not sought by the White House. A senior White House official said Gottlieb had spoken to President Trump, who liked the FDA chief and did not want him to leave. While Gottlieb had some policy disagreements with the White House, he is well respected, and could even be invited back to another post, two officials said.

 

This is also  what USA Today have just published

WASHINGTON – Food and Drug Administration Commissioner Scott Gottlieb has resigned, officials said Tuesday.

Gottlieb, 46, plans to leave the watchdog agency in a month, the Department of Health and Human Services said.

Health Secretary Alex Azar called Gottlieb “an exemplary public health leader, aggressive advocate for American patients, and passionate promoter of innovation.”

“Scott’s leadership inspired historic results from the FDA team, which delivered record approvals of both innovative treatments and affordable generic drugs, while advancing important policies to confront opioid addiction, tobacco and youth e-cigarette use, chronic disease, and more,” Azar said in a statement. “The public health of our country is better off for the work Scott and the entire FDA team have done over the last two years.”

Gottlieb, a physician and venture capitalist, was sworn in as FDA commissioner in May 2017. He previously served as the agency’s deputy commissioner for medical and scientific affairs.

As commissioner, he worked to curb youth vaping, which he declared an “epidemic” last year, and opioid addiction.

https://www.usatoday.com/story/news/health/2019/03/05/fda-commissioner-scott-gottlieb-resigns-food-drug-administration/3069901002/